Friability testing is a laboratory technique used by the pharmaceutical industry to test the durability of tablets during transit. The result is inspected for broken tablets, and the percentage of tablet mass lost through chipping.

How many Tablets shall be taken for checking friability? Ans:For tablets with unit mass equal or less than 650 mg, take sample of whole tablets corresponding to 6.5g. For tablets with unit mass more than 650mg,take a sample of 10 whole tablets. 2.

Company’s Digital Friability Test Apparatus is a precision instrument for measuring obression strength of the tablets. The Friability Test Apparatus is designed as per IP/USP standards. The unit is equipped with two transparent acrylic drums which rotate at a speed of 25 .

Friability is when a tablet has the tendency to chip, crumble or break during transportation. This can happen when the tablet is being handled, packaged or transported and may mean the patient receives an incorrect dose.

5.0 DEFINITIONS: Tablet friability can be used to measure efficiency of tabletting equipment or as an indicator of formulation suitability as well as routine QC functions. It can also be thought of as measuring “dusting”. Tablets are rotated in a plastic drum for a specified period of time.

Friability test procedure: Collect an equal amount of tablets from both sides of the chute and affix label on it. Take the tablet’s weight equal to or less than 6.5 g if the unit weight is equal to or less than 650 mg. If tablets having a unit weight of more than 650 mg, then collect ten tablets as a whole sample.

A new apparatus which measures resistance to abrasion and shock has been designed. A weighed sample of tablets is subjected in the apparatus to a tumbling action and to the shock resulting from a free-fall of six inches. The loss of weight suffered is a measure of the friability of the tablets.

Friability test: Defined as the % of weight loss by tablets due to mechanical action during the test. Tablets are weighing before & after testing & friability is expressed as a percentage loss on pre-test tablet weight.

After that, you can remove the samples from the drum, de-dust, weigh and calculate friability. The tablets are said to have passed the friability test if the average percentage weight loss is less than or equivalent to 1%. Below is a picture of a single drum tablet friability tester.

Panomex Inc. brings to you friability testers often called friabilators for accurate friability determination of compressed and uncoated tablets. These instruments are available with 1 or 2 drums as required.

Friability test of tablets, Granules, Spheroids is a technique used by the pharmaceutical company to test the durability of tablets, Granules, Spheroids during coating, packaging, and transportation.

TABLET FRIABILITY. The loss due to abrasion is a measure of the tablet friability. The value is expressed as a percentage. A maximum weight lossof not more than 1% of the weight of the tablets being tested during the friability test is considered generally acceptable and any broken or smashed tablets are not picked up.