Fruits associated with medicine interactions include orange, pomelo, pomegranate, cranberry, grape, apple, and grapefruit.

When two drugs are used together, their effects can be additive (the result is what you expect when you add together the effect of each drug taken independently), synergistic (combining the drugs leads to a larger effect than expected), or antagonistic (combining the drugs leads to a smaller effect than expected).

Drug interactions that are of greatest concern are those that reduce the desired effects or increase the adverse effects of the drugs. Drugs that reduce the absorption or increase the metabolism or elimination of other drugs tend to reduce the effects of the other drugs.

Symptoms of adverse drug reactions include:

• skin rash.
• bruising.
• bleeding.
• swelling.
• dizziness.
• severe nausea and vomiting.
• diarrhea.
• constipation.

Types of drug interactions

• Drug-drug. A drug-drug reaction is when there’s an interaction between two or more prescription drugs.
• Drug-nonprescription treatment. This is a reaction between a drug and a nonprescription treatment.
• Drug-food.
• Drug-alcohol.
• Drug-disease.
• Drug-laboratory.

5 Dangerous Food-Drug Interactions

1. Calcium-Rich Foods + Antibiotics.
2. Pickled, Cured, and Fermented Foods + MAIOs.
3. Vitamin K-Rich Foods + Warfarin.
4. Alcohol + Prescription Stimulants.
5. Grapefruit and Grapefruit Juice + Statins.

The milk interferes with the absorption of various antibiotics such as tetracycline’s (decreasing absorption) and few quinolones, propranolol, mercaptopurine (reduce bioavailability), nonsteroidal anti-inflammatory drugs, digitalis, amiloride, omeprazole, spironolactone and ranitidine.

Bananas. Don’t eat them if you take ACE inhibitors such as captopril, enalapril and fosinopril among others. ACE inhibitors lower blood pressure and treat heart failure by opening up blood vessels, so blood flows more efficiently.

What should I avoid while taking selegiline?

• air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring;
• any spoiled or improperly stored beef, poultry, fish, or liver;
• beer from a tap, beer that has not been pasteurized;

Dogs. Selegiline is the only FDA-approved treatment for canine cognitive dysfunction. Although the onset of action can be variable (between four and12 weeks), most dogs show some improvement after one month of treatment and there may be continued improvement over time.

Parkinson’s disease (PD), a neurodegenerative disorder, is accompanied by various non-motor symptoms including depression and anxiety, which may precede the onset of motor symptoms. Selegiline is an irreversible monoamine oxidase-B (MAO-B) inhibitor, and is widely used in the treatment of PD and major depression.

Transdermal selegiline, an irreversible selective monoamine oxidase B (MAO-B) inhibitor, is approved as an antidepressant in the USA. Some reports have shown that oral selegiline treatment can also be effective in treating depression.

Selegiline is in a group of medications called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine (a natural substance that is needed to control movement) in the brain.