Hemlibra® works by replacing the function of factor VIII (8), rather than replacing the missing clotting factor VIII directly. It can be used to either prevent or reduce the frequency of bleeding episodes in people with hemophilia A. This treatment product can be given by injection under the skin.

Hemophilia is a rare disorder in which your blood doesn’t clot normally because it lacks sufficient blood-clotting proteins (clotting factors).

Hemophilia can be treated by replacing missing blood clotting factors. This is called clotting factor replacement therapy. Clotting factors are replaced by injecting (infusing) a clotting factor concentrate into a vein. Infusions of clotting factors help blood to clot normally.

The following are coagulation factors and their common names:

• Factor I – fibrinogen.
• Factor II – prothrombin.
• Factor III – tissue thromboplastin (tissue factor)
• Factor IV – ionized calcium ( Ca++ )
• Factor V – labile factor or proaccelerin.
• Factor VI – unassigned.
• Factor VII – stable factor or proconvertin.

Do not wear them when you sleep. Elevate your legs above the level of your heart. Elevate your legs when you sit or lie down, as often as you can. This will help decrease swelling and pain.

Symptoms and signs of DVT occur in the leg with the blood clot, and include:

• Swelling.
• Pain.
• Redness.
• Warmth to the touch.
• Worsening leg pain when bending the foot.
• Leg cramps (especially at night and/or in the calf)
• Discoloration of skin.

Following a DVT, your leg may be swollen, tender, red, or hot to the touch. These symptoms should improve over time, and exercise often helps. Walking and exercise are safe to do, but be sure to listen to your body to avoid overexertion.

If you are currently being treated for DVT, do not massage your legs. Massage could cause the clot to break loose. If you are scheduled for surgery, ask your surgeon what you can do to help prevent blood clots after surgery.