The definition for tonic muscle activity is long-lasting activity accompanied by complex movement: 20 to 30 seconds of REM sleep epochs with abnormally elevated background activity for 50% of the epoch.

In physiology, medicine, and anatomy, muscle tone (residual muscle tension or tonus) is the continuous and passive partial contraction of the muscles, or the muscle’s resistance to passive stretch during resting state.

Definition. Hypotonia is a medical term used to describe decreased muscle tone.

Tonus is the Latin equivalent of the English word tone. It is especially used to refer to: Muscle tone, the continuous and passive partial contraction of the muscles. Arterial tone, the continuous and passive partial contraction of the arterioles. Tonicity, the ability of a solution to cause water movement.

Tonic: Producing and restoring the normal tone; characterized by continuous tension.

Medical Definition of tonic (Entry 1 of 2) 1a : characterized by tonus tonic contraction of muscle also : marked by or being prolonged muscular contraction tonic convulsions. b : producing or adapted to produce healthy muscular condition and reaction of organs (as muscles)

The definition of tonic is producing good muscle tone, or stimulating. An example of something tonic is an exercise that strengthens the arms. Tonic is defined as something that stimulates or excites, or a type of carbonated drink.

A skin tonic is a highly effective dermatological preparation, especially developed to refine and rejuvenate the skin after cleansing. It’s a combination of allantoin, saccharide isomerate, silk extract, and glyceryl triesters. It helps calm and soothes the skin, by revitalizing and renewing it.

Schweppes Tonic Water is part of the Schweppes range. It can be enjoyed on its own or combined with alcohol or fruit juice.

Schweppes Tonic Water First off, I received a very small can, 7.5 fl oz, not a bottle as pictured. Second, it contains quinine, which helps with our current situation (SarsCov2) , so that’s an added bonus. It’s refreshing, & caffeine free, but it does contain sugar, 20 g.

Even three glasses daily should be OK as long as you are not sensitive to quinine. Some susceptible people develop a dangerous blood disorder after even small doses of quinine. Symptoms of quinine toxicity include digestive upset, headache, ringing in the ears, visual disturbances, skin rash and arrhythmias.

Quinine comes from the bark of the cinchona tree. This tree is native to central and South America, as well as some islands in the Caribbean and western parts of Africa. People have consumed quinine in tonic water to help treat cases of malaria for centuries.

In early 2007, FDA banned all prescription quinine products other than Qualaquin. FDA acted in this manner because of a perception that quinine is not effective for this condition and that its risk potential far exceeds its efficacy potential.

Chloroquine is a synthetic form of quinine, a compound found in the bark of cinchona trees native to Peru and used for centuries to treat malaria.

Quinine, termed a “general protoplasmic poison” is toxic to many bacteria, yeasts, and trypanosomes, as well as to malarial plasmodia. Quinine has local anesthetic action but also is an irritant. The irritant effects may be responsible in part for the nausea associated with its clinical use.

Tonic water contains no more than 83 mg of quinine per liter—a much lower concentration than the 500 to 1,000 mg in the therapeutic dose of quinine tablets.

The juice or grapefruit itself contains valuable and natural quinine, which is advantageous for the treatment of malaria. Quinine is an alkaloid with a long history of treating malaria, as well as lupus, arthritis and nocturnal leg cramps.

Who should not take QUININE SULFATE?

• a significant complication of malaria called blackwater fever.
• low blood sugar.
• low amount of potassium in the blood.
• hemolytic uremic syndrome, a condition that affects the kidney and the blood.
• decreased blood platelets.
• myasthenia gravis, a skeletal muscle disorder.

Mild headache, flushing, unusual sweating, nausea, ringing in the ears, decreased hearing, dizziness, blurred vision, and temporary changes in color vision may occur.

Long-term off-label use of quinine, still prescribed to individuals with muscle cramps despite Food and Drug Administration warnings of adverse events, is associated with an increased risk of death, according to a study published by JAMA.

Quinine is a medication and cutting agent used to cut illicit narcotics such as heroin, it has also been used to treat malaria and babesiosis. This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.

Adults and children 16 years of age and older—648 milligrams (mg) (2 capsules) every 8 hours for 7 days. Children younger than 16 years of age—Use and dose must be determined by your doctor.

Quinine is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by mosquitos in certain parts of the world).

The FDA only allows 83 milligrams of quinine per liter bottle of tonic or quinine water. That comes out to be about 20 milligrams of quinine per 8-ounce glass.

If vitamins don’t work over time, taking antihistamines or calcium channel blockers have been shown to help those suffering from muscle cramps. If all else fails and the cramps are interfering with your day-to-day life, try drinking about 6 ounces of tonic water before going to bed.

Here we have shown, using cocaine/quinine co-administration in mice, that quinine facilitates the cocaine behavioral stimulant effect, while give no stimulation itself. Effects of quinine co-administration became more pronounced with prolonged used of cocaine for more than one week.

Quinine stimulates a specialized channel on cell membranes called TRPM7. Such transient receptor potential (TRP) channels are found on nerves throughout the body. Activating them through the TRP channels appears to reverse the nerve hyperactivity that causes muscle cramps.