Estrogen protects the adult skeleton against bone loss by slowing the rate of bone remodeling and by maintaining a focal balance between bone formation and resorption.
Q. How does estrogen affect the bones?
The main effect of estrogen is to inhibit bone remodeling, likely via the osteocyte. Estrogen also inhibits bone resorption, principally by directs effects on osteoclasts, although effects of estrogen on osteoblast/osteocyte and T-cell regulation of osteoclasts likely also play a role.
Table of Contents
- Q. How does estrogen affect the bones?
- Q. Does estrogen make bones stronger?
- Q. Why does estrogen affect bone loss?
- Q. Can Estrogen reverse bone loss?
- Q. Does estradiol help with bone loss?
- Q. Does estrogen help osteopenia?
- Q. What is best treatment for low bone density?
- Q. Can osteoporosis be reversed without medication?
Q. Does estrogen make bones stronger?
Taking estrogen can increase bone density and lower the risk of breaking bones. Estrogen alone is also called ET (estrogen therapy) and estrogen given with progesterone is also called HT (hormone therapy).
Q. Why does estrogen affect bone loss?
Estrogen deficiency increases the number of osteoclasts and decreases the number of osteoblasts resulting in overall bone resorption. Of note, fracture risk is inversely proportional to the estrogen level in postmenopausal women. Osteoblasts, osteocytes, and osteoclasts all express estrogen receptors.
Q. Can Estrogen reverse bone loss?
Estrogen replacement therapy used to be the only FDA-approved treatment to prevent osteoporosis. There are now many other drugs and medications for osteoporosis, but estrogen remains a fairly common treatment to conserve bone mass and prevent osteoporosis-related fractures in post-menopausal women.
Q. Does estradiol help with bone loss?
Previous studies demonstrated that a conventional dose of estrogen therapy (1.0 mg/d of 17β-estradiol or 0.625 mg/d of conjugated equine estrogen [CEE]) reduced bone turnover and bone loss and was associated with reduced fracture incidence in older women.
Q. Does estrogen help osteopenia?
This treatment method is often used to alleviate unpleasant symptoms associated with menopause. Because menopausal women are at a higher risk of developing osteopenia and studies have shown that estrogen can prevent bone loss in women, HRT was once considered a cure-all for osteoporosis and osteopenia in women.
Q. What is best treatment for low bone density?
Bisphosphonates are usually the first choice for osteoporosis treatment. These include: Alendronate (Fosamax), a weekly pill. Risedronate (Actonel), a weekly or monthly pill.
Q. Can osteoporosis be reversed without medication?
Can osteoporosis be reversed without medications? Your doctor diagnoses osteoporosis based on bone density loss. You can have different degrees of the condition, and catching it early can help you prevent the condition from worsening. You cannot reverse bone loss on your own.
