There is very little opportunity for the testing to benefit a young child. The incidence of venous thrombosis in healthy children is extremely low (0.07/10,000), so that long-term anticoagulation in a healthy child is unwarranted.

How is the diagnosis made? A blood test (called a screening test) can show if you have Activated Protein C resistance. If you do, another blood test that examines your genes (called DNA) will be done to find out if Factor V Leiden is the cause of the resistance and what type of Factor V Leiden you have.

Factor V Leiden (FVL) mutation and prothrombin 20210 (PT 20210) mutation tests are two tests often used together to help diagnose the cause of inappropriate blood clot (thrombus) formation, including deep vein thrombosis (DVT) and/or venous thromboembolism (VTE).

Tests to detect factor V deficiency include:

1. Factor V assay.
2. Blood clotting tests, including partial thromboplastin time (PTT) and prothrombin time.
3. Bleeding time.

A factor V test is a blood test that checks for a deficiency in a protein known as factor V. Factor V is a protein that helps your blood to clot. Having too little factor V can cause a rare bleeding disorder. Your body has many protein “clotting factors.” They are identified by Roman numerals.

Though factor V Leiden alone does not seem to raise the risk of arterial clots, something as simple as daily therapy with low-dose aspirin may help prevent a heart attack or stroke in people with factor V Leiden if they have additional risk factors.

Your doctor may suspect factor V Leiden if you’ve had one or more episodes of abnormal blood clotting or if you have a strong family history of abnormal blood clots. Your doctor can confirm that you have factor V Leiden with a blood test.

What happens during a D-dimer test? A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out.

A genetic or activated protein C (APC) resistance test or a coagulation screen (screening test) is the initial test that helps the doctor diagnose FVL.

Your doctor can diagnose FVL by ordering special screening and confirmatory blood tests that are specific to detect the presence of the mutation. Despite the fact that FVL can be diagnosed by simple blood tests, such testing is not necessary in every person with a personal or family history of DVT or PE.

Factor V Leiden thrombophilia is a relatively common condition. In some families, both parents have the F5 mutation. In this scenario, each child of the couple would have a 25% or 1 in 4 chance of having two mutations, a 25% chance of having no mutation, and a 50% chance of having a one mutation. [1]

Treatment For Factor 5 Blood Disorder. A person suffering form factor v leiden does not need any treatment if he is asymptomatic. If there are blood clots present in lower leg veins or anywhere else, blood thinning agents are usually administered to prevent clots. You may have to take these medicines for few months. Rarely surgery is opted for removing the clots.

The factor V (five) assay is a blood test to measure the activity of factor V. This is one of the proteins in the body that helps the blood clot. A blood sample is needed.

Factor V Leiden is usually diagnosed by a blood test called a coagulation screening test. However, people may also be diagnosed with a Factor V DNA Screen.