Brain contains a functional glucose-6-phosphatase complex capable of endogenous glucose production.

In the assay, glucose-6-phosphate is oxidized into an intermediate product which in turn converts the probe into an intensely colored product with an absorbance at OD=450 nm. This product can detect G6P in the range of 1-30 nmoles with a detection sensitivity ~10 µM G6P.

liver
Glucose-6-phosphatase (G6Pase), an enzyme found mainly in the liver and the kidneys, plays the important role of providing glucose during starvation. Unlike most phosphatases acting on water-soluble compounds, it is a membrane-bound enzyme, being associated with the endoplasmic reticulum.

The translocase transports glucose-6-phosphate into the lumen of the endoplasmic reticulum, where it is hydrolyzed into glucose and inorganic phosphate. Absence of translocase results in an inability to liberate glucose from glucose-6-phosphate.

Abstract. GLUCOSE-6-PHOSPHATASE and glucose-6-phosphate dehydrogenase (G6PD) are both important enzymes; a deficiency of either of these enzymes can cause the infant to have significant or life-threatening symptoms.

Phosphoglucomutase-1 is a key enzyme in glycolysis and glycogenesis by catalyzing in the bidirectional transfer of phosphate from position 1 to 6 on glucose. Glucose-1-P and UDP-glucose are closely linked to galactose metabolism. Normal PGM1 activity is important for effective glycolysis during fasting.

The classical role of glucose-6-phosphatase in liver and kidney is the production of glucose for release into blood. In liver, glucose-6-phosphatase catalyses the terminal step of glycogenolysis and gluconeogenesis.

G6PD deficiency is inherited. This means it is passed down from parents through their genes. Women who carry one copy of the gene can pass G6PD deficiency to their children.

Gene Kelly filmography. Gene Kelly (1912–1996) was an American dancer, actor, singer, director, producer and choreographer whose work in motion pictures spans from 1942 to 1996.

Gene Kelly had three children. His first was a daughter, Kerry (above), born in October of 1942 to Gene and his first wife, Betsy Blair. Although likely exaggerated (as fanzine interviews typically were/are), the Photoplay article “My Kids, The Kellys” (Feb. 1949) discusses young Kerry’s relationship with her father:

Unlike many of his Hollywood peers, Gene Kelly took his education seriously, enrolling more than once in a university. After earning a degree in economics, Kelly almost enrolled in law school. However, during the Great Depression, he had been forced to drop out of school and teach dance with his parents in order to pay the bills.

Kelly received an Academy Honorary Award in 1952 for his career achievements, the same year An American in Paris won six Academy Awards, including Best Picture. He later received lifetime achievement awards in the Kennedy Center Honors (1982), and from the Screen Actors Guild and American Film Institute.