Any blood in the urine can be a sign of a serious health problem, even if it happens only once. Ignoring hematuria can lead to the worsening of serious conditions like cancer and kidney disease, so you should talk to your doctor as soon as possible.

Anal bleeding is nearly always due to benign conditions, usually haemorrhoids (“piles”) or fissures. The blood is usually bright red and fresh as though you had been cut. It usually occurs when your bowel has been moved but is sometimes seen as a stain on the bedclothes or underwear.

Vaginal bleeding between periods is not usually a cause for concern. If the blood flow is light, it is called ‘spotting. ‘ Bleeding between periods can have a range of causes, including hormonal changes, injury, or an underlying health condition.

Bloody urine may be due to a problem in your kidneys or other parts of the urinary tract, such as: Cancer of the bladder or kidney. Infection of the bladder, kidney, prostate, or urethra. Inflammation of the bladder, urethra, prostate, or kidney (glomerulonephritis)

Common benign (non-serious) causes — If you see a small amount of bright red blood on the toilet paper after wiping, on the outside of your stool, or in the toilet, this may be caused by hemorrhoids or an anal fissure. Both of these conditions are benign, and there are treatments that can help.

The causes of hematuria include vigorous exercise and sexual activity, among others. More serious causes of hematuria include kidney or bladder cancer; inflammation of the kidney, urethra, bladder, or prostate; and polycystic kidney disease, among other causes.

Water drinking also acutely raises blood pressure in older normal subjects. The pressor effect of oral water is an important yet unrecognized confounding factor in clinical studies of pressor agents and antihypertensive medications.