to prevent symptoms, swallow 1 tablet with a glass of water at any time from 10 to 60 minutes before eating food or drinking beverages that cause heartburn. do not use more than 2 tablets in 24 hours.

How to use Pepcid Complete. Chew one tablet completely and swallow as needed to stop/prevent the symptoms of heartburn and indigestion, or take as directed by your doctor. Do not swallow the tablets whole. Do not take more than 2 tablets within 24 hours.

Adults—20 milligrams (mg) every 6 hours. Your doctor may adjust your dose as needed.

Take Famotidine Tablets once daily before bedtime or twice daily in the morning and before bedtime, as recommended. Famotidine Tablets may be taken with or without food.

What Are Side Effects of Pepcid?

• constipation,
• diarrhea,
• fatigue,
• dizziness,
• weakness,
• mood changes,
• headache,
• insomnia,

Both famotidine and omeprazole can be effective drugs for treating GERD and other digestive conditions. However, the general consensus is that omeprazole is a more potent drug than famotidine. Randomized, clinical trials have shown that PPIs are more effective in treating duodenal ulcers than H2 blockers.

Serious side effects

• Heart rate and rhythm problems. Symptoms can include: dizziness.
• Severe muscle problems. Symptoms can include: unusual muscle pain that you cannot explain.
• Neurological problems. Symptoms can include: agitation.
• Liver problems. Symptoms can include:
• Skin problems. Symptoms can include:

The FDA reported the famotidine shortage on May 4, 2020. According to the FDA, 20 mg and 40 mg famotidine tablets from manufacturers Aurobindo Pharma, Carlsbad Technology, and Teva Pharmaceuticals are in shortage. The American Society of Hospital Pharmacists (ASHP) also lists shortages of the drug.

To prevent heartburn, take 1 tablet by mouth with a glass of water 15-60 minutes before eating food or drinking beverages that cause heartburn. Do not use more than 2 tablets in 24 hours unless directed by your doctor. Do not take for more than 14 days in a row without talking with your doctor.

How To Wean Off PPIs

1. Step 1: Begin alternating between 1 PPI/day and 2 PPIs/day. On days with 1 PPI, take the PPI with your largest meal.
2. Step 2: After 2 weeks of alternating, reduce intake to approximately 1 PPI/day.
3. Step 3: After about 2 more weeks, you can try to transition off completely.

These data suggest that famotidine, unlike cimetidine, does not inhibit renal tubular secretion of creatinine. Thus, famotidine does not affect creatinine-dependent measurements of renal function and is unlikely to alter the renal elimination of basic drugs.

Famotidine, an H2-receptor antagonist with a thiazole nucleus, is approximately 7.5 times more potent than ranitidine and 20 times more potent than cimetidine on an equimolar basis.

After treatment, patients who received famotidine demonstrated cardiac function improvements, including a slight decrease in both systolic and diastolic blood pressure compared with those measures before treatment (systolic, 107±3 mmHg vs 112±3 mmHg; P<.