It’s often referred to as the mother of all cannabinoids. This is because other cannabinoids are derived from cannabigerolic acid (CBGA), an acidic form of CBG. Other more common cannabinoids obtained from cannabis plants include cannabidiol (CBD) and tetrahydrocannabinol (THC).

Vitamin B supplements Riboflavin, also known as B2, is found in hemp seed oil and may return a false THC (marijuana) reading.

Cannabigerol is not scheduled by the UN Convention on Psychotropic Substances. In the United States, CBG derived from marijuana is illegal under the Controlled Substances Act, while CBG derived from hemp is legal.

Cannabigerol, or CBG, is a non-psychoactive cannabinoid typically most abundant in low-THC and high-CBD cannabis strains, including hemp.

How many cannabinoids are there? Besides THC and CBD, more than 100 other cannabinoids have been identified.

The CB1 receptor is expressed mainly in the brain (central nervous system or “CNS”), but also in the lungs, liver and kidneys. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells, however further research has found the existence of these receptors in parts of the brain as well.

CBG can also antagonize the stimulation of serotonin 5-HT1A and CB1 receptors with significant efficiency. Older work supports gamma aminobutyric acid (GABA) uptake inhibition greater than THC or CBD that could suggest muscle relaxant properties (Banerjee, Snyder, & Mechoulam, 1975).

The endogenous cannabinoid system—named for the plant that led to its discovery—is one of the most important physiologic systems involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells.

The two main cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). The most commonly known of the two is delta-9-tetrahydrocannabinol (THC), which is the chemical that is responsible for the psychoactive effects of cannabis.