It’s best to take rabeprazole before a meal. Swallow tablets whole with a drink of water.

Grapefruit can raise the levels of budesonide in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Some sedative medications (benzodiazepines) that might interact with grapefruit juice include diazepam (Valium), midazolam (Versed), quazepam (Doral), and triazolam (Halcion). The body breaks down sildenafil (Viagra) to get rid of it. Grapefruit can decrease how quickly the body breaks down sildenafil (Viagra).

Rabeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Do not swallow the capsule whole. Take the capsule 30 minutes before a meal.

Taking rabeprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk….Common side effects may include:

• headache;
• nausea, vomiting;
• diarrhea, constipation; or.
• stomach pain.

Subsequent esomeprazole therapy did not cause psychiatric symptoms. probability scale, rabeprazole was the probable cause of the adverse reaction. PPI-induced hypergastrinemia in neuropsychiatric adverse reactions. : anxiety, hypergastrinaemia, panic disorder, rabeprazole.

Specifically, the risk of clinical depression increased for those who took the drugs pantoprazole, lansoprazole, and rabeprazole, while in those who used omeprazole and esomeprazole, “only a trend significance was noted.”

Check with your doctor right away if you have a change in frequency of urination or amount of urine, blood in the urine, fever, joint pain, loss of appetite, skin rash, swelling of the body or feet and ankles, unusual tiredness or weakness, or unusual weight gain.

It will last for one or two months if it is to allow an ulcer to heal. For all other reasons for taking rabeprazole, your treatment will last for as long as is necessary to control your symptoms.

The acid suppression effect of Pariet occurs very quickly (within 2-4 hours) and lasts up to 23 hours after the first dose. Normal acid production can be decreased by 69%. Also at 23 hours, the amount of acid produced when eating food (which is when a lot of acid is created) is reduced by 82%.

Osteoporosis fractures: Long term use of rabeprazole may be related to an increased risk of bone fractures in the hip, wrist or spine, as a result of weakened bones. This risk is further increased if you are at risk of developing osteoporosis.

The drug is efficacious in gastro-esophageal reflux disease (GERD) and other acid-related diseases. Long-term use of rabeprazole was confirmed to be safe in studies of two to five-year maintenance therapy for GERD.

How To Wean Off PPIs

1. Step 1: Begin alternating between 1 PPI/day and 2 PPIs/day. On days with 1 PPI, take the PPI with your largest meal.
2. Step 2: After 2 weeks of alternating, reduce intake to approximately 1 PPI/day.
3. Step 3: After about 2 more weeks, you can try to transition off completely.

Rabeprazole and pantoprazole (IC₅₀ = ≥ 25 μM) were the weakest.

Although PPIs were found to be more effective in treating symptoms and complications associated with GERD, H2 blockers have proven to be just as effective in suppressing gastric acid. H2 blockers are available by prescription or over-the-counter, and include ranitidine, famotidine, cimetidine and nizatidine.