Using diphenhydrAMINE together with cyclobenzaprine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems.

No interactions were found between carisoprodol and ibuprofen.

Interactions between your drugs No interactions were found between Soma and Tylenol. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No interactions were found between atorvastatin and Ibuprofen PM.

Do not take more than directed.

You can overdose on ibuprofen. You should always take it exactly as directed on the label or as recommended by your doctor. Taking too much ibuprofen, which is called an overdose, can cause dangerous side effects, including damage to your stomach or intestines. In rare cases, an overdose can be fatal.

It can take up to 24 hours to completely rid your system of ibuprofen, even though its effects generally last about 4 to 6 hours. According to the prescribing information, the ibuprofen half-life is about two hours. In case of an ibuprofen overdose, call 911 or Poison Control at 800-222-1222.

Can ibuprofen cause liver damage? Ibuprofen and other NSAIDs rarely affect the liver. Unlike acetaminophen (Tylenol), most NSAIDs are absorbed completely and undergo negligible liver metabolism. In other words, the way NSAIDs are metabolized makes liver injury ( hepatotoxicity) very rare.

How Can I Sleep Better? An over-the-counter pain reliever such as ibuprofen can help relieve some common pains that interfere with sleep (like headaches, back pain, muscle pain, and arthritis pain). In addition to ibuprofen, Advil Nighttime also includes diphenhydramine, a medicine that causes drowsiness.