Depression is known to run in families, suggesting that genetic factors contribute to the risk of developing this disease. However, research into the genetics of depression is in its early stages, and very little is known for certain about the genetic basis of the disease.

proudly refusing to obey authority: a defiant attitude/gesture. The protesters blocking the entrance to the offices remained defiant this morning. not willing to accept criticism or disapproval: The CEO was in a defiant mood as she entered the boardroom..

Physical underpinnings. Melancholia has a strong genetic contribution, with sufferers likely to report a family history of “depression”, bipolar disorder or suicide. It’s largely biologically underpinned rather than caused by social factors (stressors) or psychological factors, such as personality style.

Conflict: Personal turmoil or disputes with family or friends may lead to depression. Abuse: Past physical, sexual, or emotional abuse can bring it on, as well. Life events: Even good things, like moving or graduating, could make you depressed.

Research has found that stress caused by sleep deprivation increases signs of aging, such as fine lines, reduced elasticity, and uneven pigmentation. The loss of skin elasticity may also contribute to the formation of bags under your eyes.

If your neutral face (at rest) always look sad or angry, it means that you have dominant thought patterns that are sad or angry. Such thoughts have occurred so often, that they are now set in your face permanently. Thoughts become things. So, if we are sad often enough, that will become our permanent feature.

Wrinkles may not completely disappear, but there are ways to smooth them, boost your confidence and improve how you feel about your skin. “Keep in mind: Some of the least expensive ways to fight aging involve no creams whatsoever.

Water keeps your body hydrated and refreshed and helps maintain your skin’s elasticity. People who drink large amounts of water are less likely to suffer from scars, wrinkles, and soft lines and they won’t show as many signs of aging as those who drink little amounts of water.

Natural remedies for wrinkles

1. Aloe vera. Aloe vera has numerous healing properties.
2. Banana mask. Bananas contain natural oils and vitamins that can boost skin health.
3. Superfoods.
4. Egg whites.
5. Essential oils.
6. Massage.
7. Olive oil.
8. Topical vitamin C.