Interactions between your drugs No interactions were found between Keppra and Tylenol.

Usually, there is no interaction between AEDs and frequently used pain relief such as those containing paracetamol or ibuprofen.

Common medications that may interact with Keppra include:

• antidepressants, such as SSRIs (eg, escitalopram, fluoxetine) and monoamine oxidase inhibitors, such as isocarboxazid, selegiline, or tranylcypromine.
• antiepileptics, such as carbamazepine and phenytoin.
• benzodiazepines, such as diazepam, oxazepam, and temazepam.

What other drugs could interact with this medication?

• alcohol.
• antihistamines (e.g., cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine)
• antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone)
• azelastine.
• barbiturates (e.g., butalbital, pentobarbital, phenobarbital)

Anti-epileptic drugs (AEDs), including Keppra, increase the risk of suicidal thoughts or behavior. Patients should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual mood or behavior changes.

Keppra has a plasma half-life in adults of 7 ± 1 hour and is unaffected by either dose or repeated administration. Therefore it can take about 44 hours (5.5 x 8 hours) for Keppra to be eliminated.

Keppra contains the active ingredient levetiracetam, which is a medicine used to treat epilepsy. It works by stabilising electrical activity in the brain. The brain and nerves are made up of many nerve cells that communicate with each other through electrical signals.

March 22, 2007 – Lamictal is the best first-choice drug for partial epilepsy, while valproic acid is the best first choice for generalized epilepsy, two major clinical trials show.

Never take an extra dose to make up for a forgotten one. It’s important to take this medicine regularly. Missing doses may trigger a seizure. If you forget doses often, it may help to set an alarm to remind you.

Levetiracetam is usually taken twice a day, about 12 hours apart. Swallow the tablets whole. They may have a bitter taste when the pill is crushed. People who have trouble swallowing the pills whole can break the tablets in half, mix the tablet with food, or use the liquid form.

The usual starting dose is 500 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 3000 mg per day. Children 4 years of age and older weighing 20 to 40 kg—Dose is based on body weight and must be determined by your doctor.

Levetiracetam-induced rage is a rare neurobehavioral adverse effect of levetiracetam that is characterized by seething rage, uncontrollable anger, fits of fury, depression, violence, and suicidal tendencies. It occurs more in patients with prior mood or psychotic disturbances.

Keppra is a prescription medicine used to treat the symptoms of partial onset seizures, tonic-clonic seizures and myoclonic seizures. Keppra may be used alone or with other medications.

Common side effects of Keppra include: infection, neurosis, drowsiness, asthenia, headache, nasopharyngitis, nervousness, abnormal behavior, aggressive behavior, agitation, anxiety, apathy, depersonalization, depression, fatigue, hostility, hyperkinetic muscle activity, personality disorder, emotional lability.

Side effects other than mood disorders that most often led to discontinuation of TPM treatment were mental slowing (27.8%) and dysphasia (15.0%). Other side effects that were frequently reported were gastrointestinal complaints, paresthesia, appetite loss, skin complaints, weight loss, headache and dizziness.

The FDA recently approved Xcopri, a new treatment for partial-onset seizures. Partial-onset seizures are one of the most common types of seizures. They start on one side of the brain and can be difficult to detect. Xcopri will be available for adults 18 years and older.

This particular type of medication increases your appetite, causing you to gain 10 or more pounds. Common anti-seizure medications include: Diamox, or acetazolamide. Keppra XL/Keppra, or levetiracetam.

Many medications are used in the treatment of epilepsy and seizures, including:

• Carbamazepine (Carbatrol, Tegretol, others)
• Phenytoin (Dilantin, Phenytek)
• Valproic acid (Depakene)
• Oxcarbazepine (Oxtellar, Trileptal)
• Lamotrigine (Lamictal)
• Gabapentin (Gralise, Neurontin)
• Topiramate (Topamax)
• Phenobarbital.