As most HCC is clinically diagnosed, a false-positive diagnosis can inevitably prevail after liver resection. Furthermore, the false-positive diagnosis rate in studies performed in the early 2000s was 0.7%–3.1% (6,7,8).

Hepatocellular carcinoma does not have a characteristic appearance at US. The lesions are typically hypoechoic, but they can be hyperechoic or have mixed echogenicity. The majority of nodules that measure less than 1 cm are not hepatocellular carcinoma (8).

Ultrasonography (US) is a major, sustainable hepatocellular carcinoma (HCC) surveillance method as it provides inexpensive, real-time, and noninvasive detection. Since US findings are based on pathological features, knowledge of pathological features is essential for delivering a correct US diagnosis.

Hepatocellular carcinoma (HCC) appearance varies on MRI depending on multiple factors, such as hemorrhage, degree of fibrosis, histologic pattern, degree of necrosis, and the amount of fatty change. HCC on T1-weighted images may be isointense, hypointense, or hyperintense relative to the liver.

A single tumor 2 cm (4/5 inch) or smaller that hasn’t grown into blood vessels (T1a). It has not spread to nearby lymph nodes (N0) or to distant sites (M0). A single tumor larger than 2cm (4/5 inch) that hasn’t grown into blood vessels (T1b).

It is concluded that CC measurement of the RLL in MAL from the uppermost right hemi-diaphragm to the inferior tip of the right lobe through a horizontal line parallel to the anterior liver wall is the most accurate measurement of the organ by sonography.

Tests and procedures used to diagnose hepatocellular carcinoma include:

1. Blood tests to measure liver function.
2. Imaging tests, such as CT and MRI.
3. Liver biopsy, in some cases, to remove a sample of liver tissue for laboratory testing.

Stage IA tumors are 3 centimeters (cm) or less in size. Stage IA tumors may be further divided into IA1, IA2, or IA3 based on the size of the tumor. Stage IB tumors are more than 3 cm but 4 cm or less in size.

These are called diagnostic tests. Liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver. Liver cancer is less common in the United States than in other parts of the world. Having hepatitis or cirrhosis can increase the risk of developing liver cancer.

Several imaging modalities including ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET) and angiography are used in evaluating patients with chronic liver disease and suspected HCC.

Hepatocellular carcinoma is well documented to invade portal vein and/or hepatic vein branches. MRI with Primovist is useful for diagnosing the presence and extent of infiltrating pattern HCC. Some small HCCs can be hyperintense to background liver in the hepatobiliary phase of MRI with Primovist.

Ultrasound appearance of liver metastases can have bewildering variation, and the presence of hepatic steatosis can affect the sonographic appearance of liver lesions. Radiographic features. Ultrasound.